Snv-spectrum

Easily download and plot COSMIC signatures:

python
from snv_spectrum import get_cosmic_signatures

cosmic_signatures = get_cosmic_signatures()

fig, axes = plot_spectrum(cosmic_signatures['Signature 14


Easily construct and normalize base substitution spectra including the classic 96 trinucleotide base substitution spectra as made famous by Alexandrov _et. al._ (2013).

python
import numpy

from snv_spectrum import plot_spectrum

spectrum = Spectrum(k=3, reference_notation='pyrimidine')

for snv, count in zip(spectrum.substitutions, range(96)):
spectrum[snv] = numpy.random.randint(20)

fig, axes = plot_spectrum(spectrum, kind='density')